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Symptoms of B12 deficiency may include: Depression Fatigue Trouble concentrating Confusion Memory problems Headaches Mood changes Vitamin B12 is essential for red blood cell production, so long-term deficiency can lead to anemia, which can cause fatigue, shortness of breath, and an irregular heartbeat

A normal, healthy liver can process roughly one drink per hour, so typically, one drink will stay in your system for one hour

Results Patients on digoxin throughout had a significantly greater rate of decline in eGFR per year than patients not on digoxin throughout (mean ( standard deviation)

Choosing between them depends entirely on the specific questions your research aims to answer